Post by account_disabled on Aug 30, 2023 4:52:49 GMT
Of combining opioids and cannabinoids, but did not have the scientific quality to change clinical practice. We were really interested to explore the scientific literature to understand whether the use of therapeutic cannabinoids may be an effective strategy to help people reduce their need for high-dose opioids for pain relief.
These studies highlight the potential beneficial Switzerland Mobile Number List effects of combining opioids and cannabinoids”
RG: What did you find?
Nielsen: We found there were quite a few animal studies (nineteen in total) that examined the synergistic effects of opioids and cannabinoids, and almost all of these confirmed that by combing opioids and cannabinoids.
Much lower doses of opioids are needed for effective pain relief. For example, the dose of morphine needed was four times lower when cannabinoids were given at the same time, and for codeine it was ten times lower. While this is very powerful, we often find that results in humans are quite different from those seen in animals.
We also looked at studies with humans but didn't find as many. Most of the studies in which patients were given opioids and cannabinoids didn't specifically measure if there was a change in opioid dose, or even instructed patients not to change their opioid dose to measure the effect of cannabinoids on pain.
These studies highlight the potential beneficial Switzerland Mobile Number List effects of combining opioids and cannabinoids”
RG: What did you find?
Nielsen: We found there were quite a few animal studies (nineteen in total) that examined the synergistic effects of opioids and cannabinoids, and almost all of these confirmed that by combing opioids and cannabinoids.
Much lower doses of opioids are needed for effective pain relief. For example, the dose of morphine needed was four times lower when cannabinoids were given at the same time, and for codeine it was ten times lower. While this is very powerful, we often find that results in humans are quite different from those seen in animals.
We also looked at studies with humans but didn't find as many. Most of the studies in which patients were given opioids and cannabinoids didn't specifically measure if there was a change in opioid dose, or even instructed patients not to change their opioid dose to measure the effect of cannabinoids on pain.